VISDB Viral Integration Site DataBase

VIS ID

TVIS10016389

Fusion event

HBV-chrX integration

Validated

No

Detection method

RNA-Seq

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

1775

End

1797

Orient

-

Integrated sequence

TAGGAGGCTGTAGGCATAAATTG

Chromosome

chrX

Cytoband

q26.2

Reference genome

Start

End

131544436/132410408 (Hg38)

Orient

+

Location type

Intronic

Target gene

MBNL3 ; RAP2C-AS1

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-192-5p ; hsa-mir-493-5p ; hsa-mir-6835-3p ; hsa-mir-1277-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-4528 ; hsa-mir-5011-5p ; hsa-mir-6512-5p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-8069 ; hsa-mir-1322 ; hsa-mir-1272 ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-6892-5p ; hsa-mir-3936 ; hsa-mir-548aw ; hsa-mir-3650 ; hsa-mir-4711-3p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-3613-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-520a-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-302d-3p ; hsa-mir-520c-3p ; hsa-mir-302e ; hsa-mir-520b ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-130b-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-4295 ; hsa-mir-454-3p ; hsa-mir-130a-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-342-3p ; hsa-mir-377-3p ; hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-8064 ; hsa-mir-4783-3p ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-10b-5p ; hsa-mir-4455

Nearest miRNA

hsa-let-7f-2/Upstream/11039298; hsa-mir-105-1/Downstream/1758970;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/191844, chrX-CpG: 120/Downstream/78708

Upstream sequence

agaaaataaagtagaaagctgggaaaatgtaaggaagctattggaataatttaggtgaccaatactagttctgtggcccagaacagagcttctcaacctt

Downstream sequence

CCTTTGTCAGCCACAGTATCTTAAGAGAAACAGCTGTTTGCAGAATGACTTGCTTCTTCAAATACATACAGAGTTAGAGAGAAAAAAAAAATCCTAAATA

Target sequence

GAAAAAGCCCTACCATACATCAGAATAAGAAAAGGAACCTGGGAGGCTGCAAATTAC