Basic Information
VIS ID
TVIS10016390
Fusion event
HBV-chrX integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1442
End
1477
Orient
-
Integrated sequence
CTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTG
Host Sequence
Chromosome
chrX
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
135359743/136277584 (Hg38)
End
135359778/136277619 (Hg38)
Orient
-
Nearest miRNA
hsa-let-7f-2/Upstream/1730873; hsa-mir-105-1/Downstream/273259;
Nearest TSS
ENST00000429181/Upstream/21102; ENST00000394141/Downstream/23344;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/26017, chrX-CpG: 29/Downstream/22679
Upstream sequence
aaatgtaaggaagctattggaataatttaggtgaccaatactagttctgtggcccagaacagagcttctcaaccttggaattattgacatttgaagcagg
Downstream sequence
AGACATGTGAATAGTAATGTTAGGAATTAGTTCTGCAACCCTCTGATCTCCTTCCCCTGGGTAGAGGGCAGGGTATGGATGTGGAGGTGTCATGTGGGGA
Target sequence
AAGGTTCCTTTAGCCACTCAGAGAGCACTTTCTGC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate