Basic Information
VIS ID
TVIS10016392
Fusion event
HBV-chr1 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1779
End
1834
Orient
+
Integrated sequence
AGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTG
Host Sequence
Chromosome
chr1
Cytoband
p36.22
Reference genome
GRCh37/hg19
Start
9570959/9510900 (Hg38)
End
9571006/9510947 (Hg38)
Orient
+
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/359123; hsa-mir-101-1/Downstream/456434;
Nearest TSS
ENST00000473358/Upstream/7429; ENST00000302692/Downstream/28535;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/15307, chr1-CpG: 134/Downstream/28344
Upstream sequence
agccattgatcttaatgatgctaatgccgccttctccagcacattctttattgttttgacagtgttccccagctgaacatagctgattggcaatctagca
Downstream sequence
aaaaaaaaaaaaaaatagaagaaaagacttctagaaacactttcaccatccactacagctcaccctgaacaatgacaggtcagtgcagggtcagaAAATG
Target sequence
actccagcctgggtgacagagcaagactctgtctcacaaaaaaaaaa
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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