Basic Information
VIS ID
TVIS10016395
Fusion event
HBV-chr1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
3198
End
3233
Orient
+
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37/hg19
Start
79188295/78722610 (Hg38)
End
79188330/78722645 (Hg38)
Orient
-
Fragile sites / regions
FRA1L
Nearest miRNA
hsa-mir-101-1/Upstream/1662408; hsa-mir-11399/Downstream/6411149;
Nearest TSS
ENST00000473358/Upstream/59875; ENST00000415629/Downstream/195240;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/230779, chr1-CpG: 33/Downstream/283951
Upstream sequence
aattaatggccctaagatctgtcaacattctccatttacctcattttttcttaataacaaagactggagaattctggaggaaaatgttggagctatgtgt
Downstream sequence
TGGGGACAGGCTAGGCAACAAGTGCCTGGAGTGGAGGTGGGATGGGAAGACCGTAGGATGGAGGTGGAGCCAGAAGTGCCATCTGTGGGCAAGGAGAATT
Target sequence
TAAAAAATGCCAGATGCTTGGAAGTAAAAGAGAGA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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