Basic Information
VIS ID
TVIS10016397
Fusion event
HBV-chr1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1219
End
1254
Orient
+
Integrated sequence
CATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGC
Host Sequence
Chromosome
chr1
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
107138002/106595380 (Hg38)
End
107138037/106595415 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-101-1/Upstream/6314072; hsa-mir-11399/Downstream/1301808;
Nearest TSS
ENST00000473358/Upstream/514219; ENST00000415910/Downstream/222824;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/514148, chr1-CpG: 104/Downstream/461168
Upstream sequence
attacaggtctgagccaccaggcctggccCTTCTTTTAAGCTATATTATGTAACAGTTGGTTAATTGAAACAACCACCTGGTGGTGAGCAGTTGGTAAAG
Downstream sequence
ggaattcaaaggaaggcataacgcagatgatataaacttagacgttactacatataacttgtacttaaagctgtgggacaagataacgtctacaagggag
Target sequence
gaggtgtcagctaggaatttgataaagatcagttt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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