Fusion event
HBV-FCRL1 integration
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
AACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTT
End
157768599/157798809 (Hg38)
Nearest miRNA
hsa-mir-101-1/Upstream/862530; hsa-mir-1182/Downstream/2101170;
Upstream sequence
TAATAACTGCTGATAGAAAATGAGTGATTCTTCCAgccaggcaccataatacaggctacatgtgaattttaatccttaaaacaaagttattaggtagtta
Downstream sequence
TGTTCATTCCTGTCTGTCTTACATTCCAGAAATGTACATGTATCTTACCTACCCTAAAATACTTTAAAACTCTCAAGAGTTTTTTATATTTTCACATTTG
Target sequence
AACATCTAAAGAACTTCACCAATAACTGTTCAGTA
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.