RBM34 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016405
Fusion event
HBV-RBM34 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2981
End
3016
Orient
-
Integrated sequence
AACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTC
Host Sequence
Chromosome
chr1
Cytoband
q42.3
Reference genome
GRCh37/hg19
Start
235324056/235160741 (Hg38)
End
235324091/235160776 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
RBM34
miRNAs that regulate target gene
hsa-mir-183-5p ; hsa-mir-30a-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/854202; hsa-mir-1537/Downstream/29258;
Nearest TSS
ENST00000473358/Upstream/24627; ENST00000489692/Downstream/186;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/31669, chr1-CpG: 46/Downstream/173
Upstream sequence
ggtggctcacgcctgtaatcccaactacccgggaggctgaggcaggagaattgcctgaacccgggaggcagaggttgcagtgagccaagatcaagccact
Downstream sequence
TAAAATGAATCCTGTCTGCCCCCTTTAGAAATCACGCTTCACGCGGTAGGTAAGAAGATTGCTTTGTATGTAAGTGGTTCTAACGAGCTATTCGGGAAGA
Target sequence
CTCTCACTGGTATGTAAGAGTCATGAAAGGTTACT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate