VISDB Viral Integration Site DataBase

VIS ID

TVIS10016406

Fusion event

HBV-CCDC6 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

1612

End

1647

Orient

-

Integrated sequence

GAGACCACCGTGAACGCCCACCAAATATTGCCCAAG

Chromosome

chr10

Cytoband

q21.2

Reference genome

Start

End

61576301/59816543 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-128-3p ; hsa-mir-181a-5p ; hsa-mir-331-5p ; hsa-mir-342-3p ; hsa-mir-99a-5p ; hsa-mir-92a-3p ; hsa-mir-548c-3p ; hsa-mir-671-5p ; hsa-mir-3190-3p ; hsa-mir-6079 ; hsa-mir-142-3p ; hsa-mir-146a-5p ; hsa-mir-146b-5p ; hsa-mir-580-5p ; hsa-mir-5572 ; hsa-mir-4260 ; hsa-mir-450a-2-3p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-7109-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-2117 ; hsa-mir-6740-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6835-5p ; hsa-mir-6828-5p ; hsa-mir-6077 ; hsa-mir-873-5p ; hsa-mir-7854-3p ; hsa-mir-4264 ; hsa-mir-4797-3p ; hsa-mir-4328 ; hsa-mir-6165 ; hsa-mir-2113 ; hsa-mir-630 ; hsa-mir-5093 ; hsa-mir-4790-3p ; hsa-mir-506-5p ; hsa-mir-892c-5p ; hsa-mir-3688-3p ; hsa-mir-1252-3p ; hsa-mir-3646 ; hsa-mir-5692a ; hsa-mir-218-5p ; hsa-mir-576-3p ; hsa-mir-6833-5p ; hsa-mir-6864-5p ; hsa-mir-6126 ; hsa-mir-3148 ; hsa-mir-6124 ; hsa-mir-1252-5p ; hsa-mir-299-3p ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-512-3p ; hsa-mir-708-5p ; hsa-mir-3139 ; hsa-mir-28-5p ; hsa-mir-28-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-708-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-335-3p ; hsa-mir-4652-3p ; hsa-mir-1298-5p ; hsa-mir-4778-5p ; hsa-mir-8087 ; hsa-mir-130b-3p

Nearest miRNA

hsa-mir-1265/Upstream/2511949; hsa-mir-107/Downstream/3556414;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/106267, chr10-CpG: 22/Downstream/65526

Nearest cancer related gene

CCDC6(OG, No orient, 0)

Upstream sequence

taaataaaaatAAAGATAAACTTAGTGCTGAAGAGGTAAATAGCACTACCTCTTAGTTTTCTTCTTCTATAAGAAGTGCTCACCTATGATACCCTTTTGA

Downstream sequence

tgagaaaattactagatataattttaccatttgcaaagtaagggacaaaaataatgtctggctcattggattacagtgagcattacatttgtaaatctag

Target sequence

aatcccagctccatcaatcactagttagaaaatgt