Basic Information
VIS ID
TVIS10016409
Fusion event
HBV-chr11 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
873
End
908
Orient
-
Integrated sequence
ATTTTATGGGTTATGTCATTGGATGTTATGGGTCCT
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37/hg19
Start
7241673/7220442 (Hg38)
End
7241708/7220477 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-210/Upstream/3364301; hsa-let-7a-2/Downstream/14289;
Nearest TSS
ENST00000527297/Upstream/131415; ENST00000534653/Downstream/2456;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/130297, chr11-CpG: 140/Downstream/31049
Upstream sequence
tttgttagttgcttgtatgtcttcttttgagaagtgtctgttcatatcctttacccactttcttaaacaagtggagtgacatatgtgttcatggattgga
Downstream sequence
TAAAGAAAAGGACAGACAAAGGGAATGTAAGAGTTCCAATCTCTTTCCTGAGAATTGCATTTGACTTCAGTTAGTCACCCCTTGAACAAGTTTTAGAGGA
Target sequence
GACTTTGACAATTAGGAAGTTACTAAAATTCTCAT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate