Basic Information
VIS ID
TVIS10016413
Fusion event
HBV-chr11 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2254
End
2268
Orient
+
Integrated sequence
ATTTGGTGTCTTTCG
Host Sequence
Chromosome
chr11
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
104641593/104770866 (Hg38)
End
104641767/104771040 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10392/Upstream/920886; hsa-let-7a-2/Downstream/6576717;
Nearest TSS
ENST00000527297/Upstream/161545; ENST00000527177/Downstream/176152;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/606536, chr11-CpG: 31/Downstream/839359
Upstream sequence
gatcagtccaacgagaagtccttgcctcagaactgctcatggatgaaagggtacactgggaagaactgggttcttggaaggatccaagcataggctggac
Downstream sequence
tgtgagacagagtcttgctctgttgcccaggctggagtacagtggcacgatcttggctcactgcaacctccaccttccaggtttgagcaattctcctgtc
Target sequence
CAAGGTCACACTGAGTTTATACAGTGTACCTGTGTCTAGGTTCATGGCTTTCCAAGTATGCCATCATAAAATAGCTTGTACTATTTTACTGGGAAATTAAACCCAGGACTATAAATCAAATTCTTTGTTGCTCTTCCTGGATCATTTTTGCttttttttttttttttttttttt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate