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VISDB
Viral Integration Site DataBase
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TVIS10016422
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016422
Fusion event
HBV-MON2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1631
End
1666
Orient
+
Integrated sequence
ACCAAATATTGCCCAAGGTCTTACATAAGAGGACTC
Host Sequence
Chromosome
chr12
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
62949777/62555997 (Hg38)
End
62949812/62556032 (Hg38)
Orient
+
Location type
Intronic
Target gene
MON2
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-21-5p
;
hsa-mir-4684-5p
;
hsa-mir-522-3p
;
hsa-mir-224-3p
;
hsa-mir-6771-3p
;
hsa-mir-105-5p
;
hsa-mir-1262
;
hsa-mir-20a-3p
;
hsa-mir-217
;
hsa-mir-340-3p
;
hsa-mir-3646
;
hsa-mir-371a-5p
;
hsa-mir-371b-5p
;
hsa-mir-372-5p
;
hsa-mir-373-5p
;
hsa-mir-4701-3p
;
hsa-mir-616-5p
;
hsa-mir-6512-3p
;
hsa-mir-661
;
hsa-mir-6720-5p
;
hsa-mir-6736-5p
;
hsa-mir-6742-3p
;
hsa-mir-6776-5p
;
hsa-mir-6807-3p
;
hsa-mir-6827-3p
;
hsa-mir-6849-3p
;
hsa-mir-7853-5p
;
hsa-mir-3675-3p
;
hsa-mir-548c-3p
Nearest miRNA
hsa-mir-1228/Upstream/295543; hsa-let-7i/Downstream/47654;
Nearest TSS
ENST00000382841/Upstream/71065;
ENST00000547287/Downstream/3878;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/88922
,
chr12-CpG: 165/Downstream/46347
Nearby gene
USP15
(-149914) ;
LINC01465
(+45718) ;
Upstream sequence
ccagctacttgagaagctgaggtggaaggaatacctgagcccaggaggtcaagactgcagtgaCCATGCCTCAAAAAAAAAAAGTCTTCCTCCTAACTCT
Downstream sequence
ACCACTGCAGACAAAGAAAAGATTGAGTCTGGAGGTGGCAATATTCTCATTCATCATTCAAGGGACACCGCCGAGAAGCAATGGGCTGAGACGTGGGTAT
Target sequence
TCTTTCATCTACTGGACAGAGTTCGAGAGTCCTCT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Sample Information
×
Sample name
31656T
Sample type
Tumor
Age
45
Gender
Female
CpG Island Information
×
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