Basic Information
VIS ID
TVIS10016427
Fusion event
HBV-chr13 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
3025
End
3060
Orient
+
Integrated sequence
GCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCA
Host Sequence
Chromosome
chr13
Cytoband
q14.13
Reference genome
GRCh37/hg19
Start
47095885/46521750 (Hg38)
End
47095920/46521785 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-2276/Upstream/2325550; hsa-mir-1267/Downstream/3474630;
Nearest TSS
ENST00000623511/Upstream/35244; ENST00000478412/Downstream/31383;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/83445, chr13-CpG: 148/Downstream/31050
Nearby gene
RUBCNL(-134285) ; LRCH1(+31375) ;
Upstream sequence
TCTCCAGAACTGAATATGCAGAGGGCTTAAGGGTTCCTTTTCTAAGTAAGAGCTGTCTCACTGCTTCCTTTTTTTATtttttttttttttttatttttta
Downstream sequence
ctccaaaagtgatcaaggacctgggcctcttccaAATGGCAATCTAACATCTAAGAGGCTTTTACTTCCTGACGAATGGAGGAGCCACACTGGCTTTTTA
Target sequence
gtcacagttgagggtgggaggaaaaggtggctctc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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