Basic Information
VIS ID
TVIS10016428
Fusion event
HBV-chr13 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
3167
End
3202
Orient
+
Integrated sequence
CAGGCCATGCAGTGG
Host Sequence
Chromosome
chr13
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
66232678/65658546 (Hg38)
End
66232713/65658581 (Hg38)
Orient
-
Fragile sites / regions
FRA13B
Nearest miRNA
hsa-mir-1297/Upstream/4458666; hsa-mir-1267/Downstream/307749;
Nearest TSS
ENST00000623511/Upstream/1582535; ENST00000437777/Downstream/207593;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1814000, chr13-CpG: 92/Downstream/1571795
Upstream sequence
aatgagAGAattagtcaggataagataggctctgctgcattaacaagtgaaccccaaaatttcagcggcttaatctgacaaaaatttacttcttgcttac
Downstream sequence
ATAAACTTAAGGGCATTATATTTCCTCTTCAAATGTTGGCTGTTTCTTTAGTCATTATCTCTTTCTTGCCTGTGCTATTGTTTATTTGAAACCATATTCC
Target sequence
TCTATTCTCACTCCTTGCTTCTTTCCTTTTCCTAC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate