Basic Information
VIS ID
TVIS10016429
Fusion event
HBV-LINC00375 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1255
End
1290
Orient
+
Integrated sequence
TCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGC
Host Sequence
Chromosome
chr13
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
85662587/85088452 (Hg38)
End
85662622/85088487 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC00375
Nearest miRNA
hsa-mir-1297/Upstream/7390336; hsa-mir-1267/Downstream/2530178;
Nearest TSS
ENST00000623511/Upstream/9532; ENST00000424926/Downstream/275114;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1208690, chr13-CpG: 121/Downstream/2582827
Nearby gene
SLITRK1(-1206094) ; SLITRK6(+704299) ;
Upstream sequence
GAGAAGTTTCCCAAACCTAATGAGTGATCCAATTGCCCTTTAATCTGAATTATGATACTACAGTGAAGAGAACCAACATAATTTTTACTGACCTTTTGTC
Downstream sequence
tctcgtgcttgtcacccaggctggagtgcaatggtgcgatatcggctcactgcaacctctgccccctggattcaagcaattctcctgcctcagcctccca
Target sequence
AGAACttctttctttctttgttttttgagatggag
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate