Basic Information
VIS ID
TVIS10016431
Fusion event
HBV-chr13 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
499
End
534
Orient
-
Integrated sequence
CAACCAGCACGGGACCATGCCGGACCTGCATGACTA
Host Sequence
Chromosome
chr13
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
104590593/103938243 (Hg38)
End
104590628/103938278 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1297/Upstream/1892239; hsa-mir-1267/Downstream/3592893;
Nearest TSS
ENST00000623511/Upstream/513043; ENST00000640578/Downstream/1527589;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1091830, chr13-CpG: 29/Downstream/2554782
Upstream sequence
CTGTCCGCAAGGGCCCCTGGGAATCCTGCTGGGTAGTTGGACTGTGAGTTCTGCCTGCTATAATCCCCTCCATCCTGGATTCTTGAGAGAAAGCATTTAT
Downstream sequence
TTAAAATTTACTGATAATTCTTTAATATACATAAATACTAATGTTTATTTTCCAAATTGTCTTGTAACAGGGATCCTCATGCATTGTATGCATTATGATT
Target sequence
CCTTTGGTTAGTCCCCAAGTGATCATTATCATACT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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