Basic Information
VIS ID
TVIS10016433
Fusion event
HBV-LOC102724934 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1177
End
1731
Orient
-
Integrated sequence
CCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGT
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37/hg19
Start
29829215/29360009 (Hg38)
End
29829656/29360450 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC102724934
Nearest miRNA
hsa-mir-208a/Upstream/1726731; hsa-mir-1185-1/Downstream/1654196;
Nearest TSS
ENST00000550708/Upstream/381085; ENST00000549515/Downstream/29896;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/574146, chr14-CpG: 147/Downstream/566554
Nearby gene
LINC01551(-565655) ; PRKD1(+216031) ;
Upstream sequence
CAAAAACTGAAGACTGTGAGAGAGGGTCAGCTTACAGGCCAGAAACTGACAATAAGATTGATGTTCAAATAGCTGAATTATTGATTCTTATCCTGAGATC
Downstream sequence
CAGTTTCTTTAAGAACCTTAGTCATTCATCTTTCCGAGATTAATATTAAAATTGTCTTAGACAAATGCCATACACTAATTGGCACTTTTCAAGTCCCTCC
Target sequence
CTACTCTATTAAAGTGCCTAAAAAAGAAAAAGAAACCCACCTAATAGTGCTAAACCCTGTAATATAAAACTGTCAACATATATATTAAAATTCTACTCTTCTAATAGTTACTATCTGGCTCGTTATCTTTATATACTAACATTGTCACAGTTAACTCACTCTCTATCAAATATAGGAACAGAATGATACAACATGGGATGAGCCAGATATGATCAGATAACTTTTAATCTATGCAATTGTGAATCTCATATTAAT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate