Basic Information
VIS ID
TVIS10016436
Fusion event
HBV-chr14 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1103
End
1138
Orient
-
Integrated sequence
CCAACTTACAAGGCCTTTCTGTGTAAACAATACCTG
Host Sequence
Chromosome
chr14
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
89363318/88896974 (Hg38)
End
89363353/88897009 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1260a/Upstream/11630684; hsa-mir-1185-1/Downstream/5051217;
Nearest TSS
ENST00000550708/Upstream/55489; ENST00000637466/Downstream/116377;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/71963, chr14-CpG: 111/Downstream/129782
Upstream sequence
tgtcatattatctttttcttacatagccttatgaggcagatattaatattacattttaaagatgatgaaatttaggcttaaagccagtgattgtatccta
Downstream sequence
ctgtctcaaaaaaaaaaagaaaaagaaaaaaaaaaagaaaaaCTTCAAgctgggcacagtggctcactcctgtaaactcagcactttgggaggctgaggc
Target sequence
cattgcactccagcctggagtgacagagcgagact
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate