VISDB Viral Integration Site DataBase

VIS ID

TVIS10016437

Fusion event

HBV-chr15 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

2900

End

2935

Orient

-

Integrated sequence

CAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAAT

Chromosome

chr15

Cytoband

q22.2

Reference genome

Start

End

60922173/60629974 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

RORA ; RORA-AS1

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-106b-5p ; hsa-mir-92a-3p ; hsa-mir-33b-5p ; hsa-mir-129-5p ; hsa-mir-32-3p ; hsa-mir-1179 ; hsa-mir-374a-5p ; hsa-mir-374b-5p ; hsa-let-7f-2-3p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-let-7a-3p ; hsa-let-7b-3p ; hsa-let-7f-1-3p ; hsa-mir-98-3p ; hsa-mir-3611 ; hsa-mir-5580-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-670-3p ; hsa-mir-4698 ; hsa-mir-548aw ; hsa-mir-190a-3p ; hsa-mir-1277-5p ; hsa-mir-5011-5p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-3662 ; hsa-mir-942-5p ; hsa-mir-506-5p ; hsa-mir-137 ; hsa-mir-218-5p ; hsa-mir-127-5p ; hsa-mir-7843-3p ; hsa-mir-4668-5p ; hsa-mir-3613-5p ; hsa-mir-4786-3p ; hsa-mir-4635 ; hsa-mir-4781-3p ; hsa-mir-4538 ; hsa-mir-4453 ; hsa-mir-7109-3p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-758-3p ; hsa-mir-1290 ; hsa-mir-876-5p ; hsa-mir-3167 ; hsa-mir-3171 ; hsa-mir-873-5p ; hsa-mir-1246 ; hsa-mir-8076 ; hsa-mir-144-3p ; hsa-mir-101-3p ; hsa-mir-4536-5p ; hsa-mir-3924 ; hsa-mir-1277-3p ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-621 ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-519e-3p ; hsa-mir-515-3p ; hsa-mir-33b-3p ; hsa-mir-3646 ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-18a-5p ; hsa-mir-4735-3p ; hsa-mir-18b-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-526b-3p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-2054 ; hsa-mir-7848-3p ; hsa-mir-4641 ; hsa-mir-656-3p ; hsa-mir-504-5p ; hsa-mir-10a-5p ; hsa-mir-10b-5p ; hsa-mir-155-5p ; hsa-mir-4775 ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-483-3p ; hsa-mir-4725-5p ; hsa-mir-4750-3p ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-6765-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-377-3p ; hsa-mir-449c-3p ; hsa-mir-6740-3p ; hsa-mir-8086 ; hsa-mir-6870-3p ; hsa-mir-622 ; hsa-mir-154-3p ; hsa-mir-4643 ; hsa-mir-466 ; hsa-mir-4789-3p ; hsa-mir-485-3p ; hsa-mir-487a-3p ; hsa-mir-539-3p

Nearest miRNA

hsa-mir-10393/Upstream/1458677; hsa-mir-11181/Downstream/1674684;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/36788, chr15-CpG: 32/Downstream/597448

Upstream sequence

AGGAGGTTACAGCTGAGTTGGGGCAAAAGAAGAGATTCCCACAAACAGCGCAAGGCAGCATTCACTTGAGGCCAGATGCTGGACCCAGTCTCAGGACTGA

Downstream sequence

AAGAAAAAGGGAACTCTGGTGAATACTTCTGAATGACAAAGATAAAATGGAAGACCTATGATTTGGCTATTGGGCTATAAAAATGGACAGCCATCACATG

Target sequence

CAGCCTAACTTCCATGGTGTTGTCACAAGCCCAAG