Basic Information
VIS ID
TVIS10016440
Fusion event
HBV-chr15 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2580
End
2615
Orient
+
Integrated sequence
ATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGA
Host Sequence
Chromosome
chr15
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
88308333/87765102 (Hg38)
End
88308368/87765137 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10393/Upstream/1939372; hsa-mir-11181/Downstream/181069;
Nearest TSS
ENST00000557528/Upstream/61250; ENST00000569588/Downstream/167953;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/1924218, chr15-CpG: 36/Downstream/490286
Nearby gene
LINC00052(-185416) ; NTRK3(+111654) ;
Nearest cancer related gene
NTRK3(OG, +111654) ;
Upstream sequence
cttttgggttaggcaaacctggatctttgtcctcgccctgccgctgagctgtggaacttggcacgttcttgggttctttgagcctcaattttcccttcat
Downstream sequence
AGTAGCCAGGGGCCCAGAATGATTCATGCTCAGTTTGACATTTAATGTCTCAAGGCTTAACTCACTTCCCCTGTCTCCTCACTTTGCCATGCTCATTTCA
Target sequence
TTGGAAGTCAAGAGTTCCTTTCTACTGGGCTTCTG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate