Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016442
Fusion event
HBV-SV2B integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1685
End
1720
Orient
-
Integrated sequence
CAACGACCGACCTTGAGGCATACTTCAAAGACTGTT
Host Sequence
Chromosome
chr15
Cytoband
q26.1
Reference genome
Start
End
91823716/91280486 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-574-5p ; hsa-mir-297 ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-5011-5p ; hsa-mir-6842-3p ; hsa-mir-647 ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-6762-3p ; hsa-mir-604 ; hsa-mir-3130-3p ; hsa-mir-6071 ; hsa-mir-8077 ; hsa-mir-7160-5p ; hsa-mir-4663 ; hsa-mir-3692-5p ; hsa-mir-27b-5p ; hsa-mir-93-3p ; hsa-mir-6728-3p ; hsa-mir-4714-3p ; hsa-mir-4789-5p ; hsa-mir-8066 ; hsa-mir-4803 ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-6716-5p ; hsa-mir-4790-3p ; hsa-mir-4518 ; hsa-mir-1266-5p ; hsa-mir-3664-3p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-211-3p
Nearest miRNA
hsa-mir-10393/Upstream/1273610; hsa-mir-1302-10/Downstream/1623913;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/179979, chr15-CpG: 40/Downstream/16232
Upstream sequence
GCTTGCTGGCAACCTCACTCTGAATTCCTTTAGTCAGTGCAAACTCTAAGGCACAGAGAGGAGTAAGAGAGAATAGAGCAGTATGACTGTGGGTGCCCAG
Downstream sequence
TGAATGAATAGAAGAATGAAAGAAAGTGTTGTAATTATTTGCAAATGAAGACATATTTAAAGGCTTCCAGCCTAAAAGTTTGACCAAGCTTGTTAAATAT
Target sequence
CATGCTCAGTGTTTGCAGAAGACTAAATATGTAAG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.