Fusion event
HBV-RBFOX1 integration
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
ACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTT
End
6006497/5956496 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1225/Upstream/323895; hsa-mir-11401/Downstream/5349944;
Upstream sequence
AGATTTTTTTCTCTTCACTTTTCTCTTCCTGTACCcacagctccggtccccatctctcccctttcccctaactttatttttgtttctgagcacttatcaa
Downstream sequence
tcctgttaaaaatgcaaatcactgggcttcctctctgagattctgattaagttagatgtggggtggAAAACAGGCAGTGGGCTGCTGGTGCTTGTGATAG
Target sequence
ACTGTACAGTCAAATTTACATgaatgccctggagc
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.