VISDB Viral Integration Site DataBase

VIS ID

TVIS10016448

Fusion event

HBV-NFAT5 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

1373

End

1408

Orient

-

Integrated sequence

CCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTG

Chromosome

chr16

Cytoband

q22.1

Reference genome

Start

End

69690187/69656284 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-31-5p ; hsa-mir-24-3p ; hsa-mir-335-5p ; hsa-mir-21-5p ; hsa-mir-877-5p ; hsa-mir-652-3p ; hsa-mir-17-5p ; hsa-mir-211-5p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-4690-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-103a-2-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-580-5p ; hsa-mir-651-3p ; hsa-mir-889-3p ; hsa-mir-1252-5p ; hsa-mir-4476 ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-6815-3p ; hsa-mir-6826-5p ; hsa-mir-6876-5p ; hsa-mir-3910 ; hsa-mir-548an ; hsa-mir-1468-3p ; hsa-mir-548p ; hsa-mir-921 ; hsa-mir-3174 ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-6507-3p ; hsa-mir-4796-3p ; hsa-mir-374a-5p ; hsa-mir-155-5p ; hsa-mir-7111-5p ; hsa-mir-6883-5p ; hsa-mir-6825-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-766-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-1827 ; hsa-mir-4419a ; hsa-mir-5681a ; hsa-mir-205-5p ; hsa-mir-4536-5p ; hsa-mir-6770-5p ; hsa-mir-6073 ; hsa-mir-1253 ; hsa-mir-552-3p ; hsa-mir-6768-5p ; hsa-mir-6505-5p ; hsa-mir-6844 ; hsa-mir-9-5p ; hsa-mir-1-3p ; hsa-mir-206 ; hsa-mir-613 ; hsa-mir-6124 ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-3202 ; hsa-mir-4756-5p ; hsa-mir-3179 ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6760-5p ; hsa-mir-6873-5p ; hsa-mir-4797-3p ; hsa-mir-6512-5p ; hsa-mir-3941 ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-4261 ; hsa-mir-4496 ; hsa-mir-146a-5p ; hsa-mir-3180-5p ; hsa-mir-345-5p ; hsa-mir-4256 ; hsa-mir-4706 ; hsa-mir-4749-5p ; hsa-mir-4762-3p ; hsa-mir-520a-5p ; hsa-mir-525-5p ; hsa-mir-6731-3p ; hsa-mir-744-5p ; hsa-mir-1273h-5p ; hsa-mir-17-3p ; hsa-mir-30b-3p ; hsa-mir-3160-3p ; hsa-mir-3192-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-3689d ; hsa-mir-4311 ; hsa-mir-4443 ; hsa-mir-4487 ; hsa-mir-485-5p ; hsa-mir-490-3p ; hsa-mir-558 ; hsa-mir-6134 ; hsa-mir-6499-3p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-6884-5p ; hsa-mir-7106-5p ; hsa-mir-7847-3p ; hsa-mir-7851-3p

Nearest miRNA

hsa-mir-1225/Upstream/90381; hsa-mir-11401/Downstream/276797;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/89416, chr16-CpG: 19/Downstream/70106

Upstream sequence

ggatggtctcaatctcctgacctcatgatctgcctgccttgacctcccaaagtgctggggttacaggcgtgagccaAGAAAACAGAACTTTTAAATGATG

Downstream sequence

aaaaaaaaaaaaaaaaaagaaTTCCCGTGGTAAAGGCAGGGAAATCAAAGCCAAGTGGAAAGCTGGCCAAAGACTTACTTTTTTGGGTTTATAATAGTAA

Target sequence

caagctgggcaacaaagcgagactctgtctcacaa