TNFRSF13B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016451
Fusion event
HBV-TNFRSF13B integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1256
End
1291
Orient
+
Integrated sequence
CCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCT
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
16845985/16942671 (Hg38)
End
16846020/16942706 (Hg38)
Orient
+
Location type
Intronic
Target gene
TNFRSF13B
miRNAs that regulate target gene
hsa-mir-877-3p ; hsa-mir-8057 ; hsa-mir-6509-3p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-661 ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-4772-3p ; hsa-mir-1304-3p ; hsa-mir-1273g-3p ; hsa-mir-181a-2-3p ; hsa-mir-6890-3p ; hsa-mir-6742-3p
Nearest miRNA
hsa-mir-1253/Upstream/660583; hsa-mir-10226/Downstream/870774;
Nearest TSS
ENST00000595228/Upstream/1609; ENST00000419151/Downstream/29372;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/251838, chr17-CpG: 117/Downstream/99364
Nearby gene
KRT16P2(-109873) ; MPRIP(+100086) ;
Upstream sequence
caattaaagttggcacaagatggaCATGTTTTATTAAAAACTGAGTGTTTTAAAGAAATACGTCACTcaggtgtggtagctcccacctgtaatcccagca
Downstream sequence
GAAATGAACGGCGTTGATTCAAGGAGGAAAACTAAACATTTGTGCATATTTCAAACATTTCATCATAAGATTCTGAAACCCAGCTTTCAGAGACCATGCA
Target sequence
AGACAGAATGCCAGGCTACAGGTTGTTACTAAGCG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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