Basic Information
VIS ID
TVIS10016452
Fusion event
HBV-chr17 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1532
End
1567
Orient
-
Integrated sequence
TCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCAT
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
21870320/22343714 (Hg38)
End
21870355/22343749 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1180/Upstream/2999140; hsa-mir-10226/Downstream/4950161;
Nearest TSS
ENST00000595228/Upstream/44339; ENST00000612344/Downstream/62270;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/126193, chr17-CpG: 27/Downstream/91625
Upstream sequence
GTAGCATCCAAAAATTTCACTAGATTACTTCATAATGGAGGATGAATCCCAAGTGTCTAGGATCCTCCATTAAATTCTTGACAGAAGACCCACAAAGATC
Downstream sequence
caggctagagggcagtggcatgatctcggctcactgcaacatccacctcccagattcaagtgattctcctgcctcagcctccagagtagctgagattaca
Target sequence
tttttctttttgagacaaagtattgctctgtcacc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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