Basic Information
VIS ID
TVIS10016458
Fusion event
HBV-chr18 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
57
End
92
Orient
+
Integrated sequence
CCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCT
Host Sequence
Chromosome
chr18
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
61544794/63877560 (Hg38)
End
61544829/63877595 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1-2/Upstream/5426402; hsa-mir-5011/Downstream/3203989;
Nearest TSS
ENST00000575820/Upstream/5868; ENST00000443281/Downstream/10105;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/454436, chr18-CpG: 63/Downstream/58571
Upstream sequence
ttagccaggcttggtggtgggcacctgtaatcccaactactcggaaggctgaggcaggagaactgcttgaacccaggaggtggaggttgcagtgagccaa
Downstream sequence
tttctcaagtagctcctggagcatgtgctgcttaaaaatgagtcagggaaccatgaagaggatgataaaaagatgtagggaaaagagaagccgacccaag
Target sequence
tctcagaaagctttctccccatgcctttttttttt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate