Basic Information
VIS ID
TVIS10016459
Fusion event
HBV-LINC01898 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1029
End
1064
Orient
-
Integrated sequence
TTACACAATGTGGTTATCCTGCGTTGATGCCTTTGT
Host Sequence
Chromosome
chr18
Cytoband
q23
Reference genome
GRCh37/hg19
Start
73415350/75703395 (Hg38)
End
73415385/75703430 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC01898
Nearest miRNA
hsa-mir-1-2/Upstream/2850013;
Nearest TSS
ENST00000575820/Upstream/266438; ENST00000581750/Downstream/8955;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/247430, chr18-CpG: 86/Downstream/212532
Upstream sequence
caaatttggagcaataatatttttaaatctaggattgtatacatcaccaaattaccaatttggtgaaagagagagatgaagcattttcagacatttatga
Downstream sequence
GGGTCTGATCTTCCCTGAGGTTGTGTCTTCTGGAAACGTGGGTGGCAGTAATTAAATATCTGTGGCCCCCTTGGTTCCTCAGGATGAATGTTCTTCTATA
Target sequence
TAGGACCAGAGCAGAACTGACCAGTGCCTGCCCTG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate