Basic Information
VIS ID
TVIS10016462
Fusion event
HBV-chr19 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1430
End
1465
Orient
+
Integrated sequence
GTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCT
Host Sequence
Chromosome
chr19
Cytoband
q13.43
Reference genome
GRCh37/hg19
Start
58300895/57789527 (Hg38)
End
58300930/57789562 (Hg38)
Orient
-
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-let-7e/Upstream/2401285; hsa-mir-10394/Downstream/545126;
Nearest TSS
ENST00000633603/Upstream/19831; ENST00000594328/Downstream/23842;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/2777, chr19-CpG: 41/Downstream/24925
Nearby gene
ZNF586(-8911) ; ZNF552(+17554) ;
Upstream sequence
gtgtgttctcatcatctagctcccacatgtaagtgagaaaatgtggtatttggtttccttttcctgcattagtttgctaaagataatggcctccaacttc
Downstream sequence
tttcaagggaatcaggggctatcacaccttcttgattcagaaaagcttacataccacagtccctggttgctctctcttatgcatagtgcaacccccatgt
Target sequence
ctgtctcaaaaattaaaaacaagccagttgcatcc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate