Basic Information
VIS ID
TVIS10016464
Fusion event
HBV-chr2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1210
End
1245
Orient
-
Integrated sequence
GGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAAC
Host Sequence
Chromosome
chr2
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
23495765/23272894 (Hg38)
End
23495800/23272929 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-3125/Upstream/3924389; hsa-mir-10b/Downstream/2055711;
Nearest TSS
ENST00000437798/Upstream/73838; ENST00000415245/Downstream/59115;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/2228805, chr2-CpG: 256/Downstream/111929
Upstream sequence
taatgattgcatccctgccttccatacactgccataagaggcaaggagaggtgagggtctcatgggaagaatagaagagaggtctcattcacataaggga
Downstream sequence
ACAAGCATGTAGATGTTTTATTTGGACTTTGTAACACTTAGATATCAGAACTGTAGGATCATCttatttttctacatcatatttaacctgactccaggcc
Target sequence
CCCTCCAGTTATGTTTAGAGAACCTGTCCATTCTG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate