Basic Information
VIS ID
TVIS10016466
Fusion event
HBV-LOC107985902 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1731
End
1766
Orient
-
Integrated sequence
CTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGT
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
79429347/79202221 (Hg38)
End
79429382/79202256 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC107985902
Nearest miRNA
hsa-mir-1285-2/Upstream/4111307; hsa-mir-10b/Downstream/447038;
Nearest TSS
ENST00000437798/Upstream/16990; ENST00000467488/Downstream/79208;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/208755, chr2-CpG: 65/Downstream/310314
Upstream sequence
CTCTCCTAAACTATTCGGCTCAGATCGCTTAATTTTTCCACCCATATCCTTTCAAGATAACAGAAATACTTCTGCATTAATCCTTGTCCTTAGTCTTTCA
Downstream sequence
agtctcaagatttattttcctttcacaGTACTCTCAGTCAGATTTCAAAAAAGATAATTTCCACACACTTGtttttttattttttttattttttttattt
Target sequence
cagcttgattttcttctttagcttggtgattttgg
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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