Basic Information
VIS ID
TVIS10016468
Fusion event
HBV-LINC01885 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1610
End
1645
Orient
+
Integrated sequence
TGGAGACCACCGTGAACGCCCACCAAATATTGCCCA
Host Sequence
Chromosome
chr2
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
108124622/107508166 (Hg38)
End
108124657/107508201 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LINC01885
Nearest miRNA
hsa-mir-1285-2/Upstream/5075800; hsa-mir-10b/Downstream/1633289;
Nearest TSS
ENST00000437798/Upstream/126974; ENST00000439893/Downstream/21286;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/620406, chr2-CpG: 16/Downstream/36044
Nearby gene
ST6GAL2(-621094) ; RGPD4-AS1(+314862) ;
Upstream sequence
CATCTCCCTCCTCACTCAGCTCATATTCCACCCGGAATCCCGACACGGTGTCGGAAGCTGAGACCCAGGAGACCACAAAGCTACTGGCTGTGATTTCGGT
Downstream sequence
TGCCTCATCCCTTGGCCTCACAATGAAATATGCACCGTTATCCTGAGTTGCTGCCTCCCTGTCACAGATACCAATACCTAGGTTATAAAGCTAACTTAGA
Target sequence
TACAGGCCAGTTATTTGCTGTTCTTACATCTGCCC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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