Basic Information
VIS ID
TVIS10016471
Fusion event
HBV-LOC101927709 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1916
End
1951
Orient
-
Integrated sequence
TTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTC
Host Sequence
Chromosome
chr2
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
119360235/118602659 (Hg38)
End
119360270/118602694 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC101927709
Nearest miRNA
hsa-mir-1285-2/Upstream/4881291; hsa-mir-10b/Downstream/8820843;
Nearest TSS
ENST00000437798/Upstream/416273; ENST00000412481/Downstream/231915;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/377769, chr2-CpG: 29/Downstream/171795
Upstream sequence
aattatatCTTGACGAAGGAGGAATCTGAGATCAGCTATTAGGTAAAAGAAATGACTCCATTCTAAATCTTTCAATTCTACCTTATGCTTTTGAAGCAAA
Downstream sequence
AGGGGAAGATCTGGGTGGCTGTGAAAGCCTCAGGCTGGTGACCAGGCTGAGCATGATGGCAAAGGTGGCCTGTTCCTCTTTGGGGGTTGAGGATATGATC
Target sequence
AGAATATGGAATCTCTACACTCCAGGAGAAAGGTG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate