Basic Information
VIS ID
TVIS10016472
Fusion event
HBV-LOC101927764 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
620
End
655
Orient
-
Integrated sequence
CTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTC
Host Sequence
Chromosome
chr2
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
120491911/119734335 (Hg38)
End
120491946/119734370 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC101927764
Nearest miRNA
hsa-mir-1285-2/Upstream/6012967; hsa-mir-10b/Downstream/7689167;
Nearest TSS
ENST00000437798/Upstream/55132; ENST00000460162/Downstream/25261;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/54901, chr2-CpG: 86/Downstream/25120
Nearby gene
TMEM177(-52217) ; PTPN4(+25295) ;
Upstream sequence
atcaaacacTGATTCCATCTGTGCTCATACCCGTCTTTAAGAAACACAGGAACCAGTTGGGTGACCACTTAAGAGTACCTGGTCACCAGGGGCAAACCTC
Downstream sequence
CTCCTGAAAGTGAGCTCAGGCTGTCCATCTTCCCTGAAGTCCAGTCCATCCCTTGCAAAGCCAGTTTCCGCTATCCCATCATGATTAATGCTGAAGCTCT
Target sequence
AATGACAGCCCTGACTGATCTCCTGAAAGTGAGCT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate