RNF25 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016478
Fusion event
HBV-RNF25 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1552
End
1587
Orient
-
Integrated sequence
GTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTT
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
219535445/218670722 (Hg38)
End
219535480/218670757 (Hg38)
Orient
+
Location type
Intronic
Target gene
RNF25
miRNAs that regulate target gene
hsa-mir-615-3p
Nearest miRNA
hsa-mir-10b/Upstream/268000; hsa-mir-1244-1/Downstream/152333;
Nearest TSS
ENST00000437798/Upstream/2554; ENST00000468026/Downstream/1210;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/10868, chr2-CpG: 31/Downstream/930
Upstream sequence
aatgattagcagaggaagcaatgacacatgcatttgtctcaggtaagcctcagagggatgactgaatagaatgggaagcaggtttaccttaaacagttcc
Downstream sequence
agaatctaaggtgtggagtcagacagatatggatttctattcataattttctatcttttggcaaatcactttacttctttgggactcaTCTAGTCTTCCC
Target sequence
TGGGGGAGTGGGGACTGAAGAATGTCCTagtacaa
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate