Basic Information
VIS ID
TVIS10016479
Fusion event
HBV-chr2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1123
End
1158
Orient
+
Integrated sequence
GTGTAAACAATACCTGAACCTTTACCCCGTTGCCCG
Host Sequence
Chromosome
chr2
Cytoband
q37.1
Reference genome
GRCh37/hg19
Start
232464106/231599395 (Hg38)
End
232464141/231599430 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10b/Upstream/236602; hsa-mir-1244-1/Downstream/113884;
Nearest TSS
ENST00000437798/Upstream/6494; ENST00000440384/Downstream/107465;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/68769, chr2-CpG: 50/Downstream/5006
Nearby gene
TEX44(-5112) ;
Upstream sequence
ACGAGCTATGCAATCTCTAAGTAGAAATAACCCCTACCTCTGGGTTTGTGGTAAAAGTTAAAATTTGACAGTCTATTATGCTAATATTTGGCCTAGATGA
Downstream sequence
atatgccactttggcataaggatgatttgagctgaaggcaattgagaaaaagcagacaggatgagctttctgccctttccctttctgcctgaaaaacagg
Target sequence
ACCTGGGCTTGAAGGCATAGGGGACCACccccaaa
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate