Basic Information
VIS ID
TVIS10016481
Fusion event
HBV-chr20 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2791
End
2826
Orient
-
Integrated sequence
ACAACACATAGCGCCTCATTTTGTGGGTCACCATAT
Host Sequence
Chromosome
chr20
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
8996717/9016070 (Hg38)
End
8996752/9016105 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-103a-2/Upstream/1644378; hsa-mir-1-1/Downstream/1633531;
Nearest TSS
ENST00000382410/Upstream/53762; ENST00000416836/Downstream/52658;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/883125, chr20-CpG: 107/Downstream/52206
Upstream sequence
AAACCAAACAGAAGCTGAGTGACCAACCTCCCCACCCCCATCACACTCAGCAGGCTGAGCAGAGTCACAGAACACACACACCTGGGTGGAACAGATGGCA
Downstream sequence
ACCTGTGTGCAAAATACTCTTGTTACTTTATCAGTCTAATAATAACAGGCCTCACTCTCACAATTCTGAACTCAGAGGATACATGTATTTGGTTTGAGGA
Target sequence
tgacACTGCATTGACATATGCATTGAGTAGATACC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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