GZF1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016483
Fusion event
HBV-GZF1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2624
End
2659
Orient
+
Integrated sequence
GATTGCAATTGATTATGCCTGCCAGGTTTTATCCAA
Host Sequence
Chromosome
chr20
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
23350770/23370133 (Hg38)
End
23350805/23370168 (Hg38)
Orient
-
Location type
Intronic
Target gene
GZF1
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-30c-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/4899442; hsa-mir-1-1/Downstream/2838018;
Nearest TSS
ENST00000382410/Upstream/1262; ENST00000619238/Downstream/51246;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/4120, chr20-CpG: 99/Downstream/50303
Nearby gene
NXT1(-15362) ; NAPB(+4385) ;
Upstream sequence
GAGCAGTGCCAGCCCCACCGCAACTGCACGGCCCTGGGCCTGGCCCTCAATGTGCCAGGCTCTTCCTCCCATGACACCCTGTGCACCAGCTGCACTGGCT
Downstream sequence
ACTGAACAGCCTGACGAAGAGTATGTGTCATCCAAGCTTTCGGATAAATTGCTGTCTTTTGCAGAAAATGGCCATTTCCACAACCTGGCTGCAGTCCAAG
Target sequence
TAGATGGCTCGCCCAAGAACGATGACGGACACAAG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate