Basic Information
VIS ID
TVIS10016484
Fusion event
HBV-chr20 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1444
End
1479
Orient
-
Integrated sequence
GAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGG
Host Sequence
Chromosome
chr20
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
31332821/32745015 (Hg38)
End
31332856/32745050 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-103a-2/Upstream/507168; hsa-mir-1-1/Downstream/1304069;
Nearest TSS
ENST00000382410/Upstream/1018; ENST00000456297/Downstream/17335;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/1389, chr20-CpG: 116/Downstream/17151
Nearby gene
COMMD7(-1007) ; DNMT3B(+17369) ;
Nearest cancer related gene
DNMT3B(TSG, +17369) ;
Upstream sequence
ATAAGGAATGGGTAAGGAATGTCTTACCCATAAGGAATGTcctccctgagaatgggctggcctcagtgactctgttctcatgaatagaatgtggcagaag
Downstream sequence
ccataaaaaaaaaagaaGGTCTGCTGTGAGGCAGATACCATGACATGATAGGGGGTGGGGATTCCACAGTGACACAACCAGATGAACCAGATGCAGTGCC
Target sequence
cactccagcctgggcgacagagcaagaccacatct
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate