Basic Information
VIS ID
TVIS10016487
Fusion event
HBV-chr20 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1026
End
1061
Orient
-
Integrated sequence
CTTTTACACAATGTGGTTATCCTGCGTTGATGCCTT
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
42870381/44241741 (Hg38)
End
42870416/44241776 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-103a-2/Upstream/3072663; hsa-mir-1-1/Downstream/166344;
Nearest TSS
ENST00000382410/Upstream/26843; ENST00000372952/Downstream/5323;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/30498, chr20-CpG: 64/Downstream/69034
Nearby gene
GDAP1L1(+5358) ;
Upstream sequence
Agtggcacatgcctgtggtcccagctactcggaggctgaggcaagaggatcacttgagatcttgagatcgagactgcagtgaacccagatggcgccactg
Downstream sequence
ctgatgatgactgcctgtatgccccactcttcccactcaatgcacatcagctgacccctagctggcaacacccatgtttattgcccgagggctttctgtg
Target sequence
cccacaagcctctgcttcaagtccctgagcagatg
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate