Basic Information
VIS ID
TVIS10016488
Fusion event
HBV-chr20 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1313
End
1348
Orient
-
Integrated sequence
GGAGCAAACATTATCGGGACTGATAACTCTGTTGTC
Host Sequence
Chromosome
chr20
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
57948208/59373153 (Hg38)
End
57948243/59373188 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-103a-2/Upstream/554840; hsa-mir-1-1/Downstream/935286;
Nearest TSS
ENST00000382410/Upstream/8380; ENST00000443747/Downstream/142003;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/72082, chr20-CpG: 31/Downstream/30558
Upstream sequence
gcaatgcagagtattgaagttaagtccaaggtcaagcacacaaGTGGGTAAAACTGAACATATGAAATGGGTGTGTGGCTGGCACCCACCTCTGACCTTT
Downstream sequence
TTGATTTACACAGGCTCTCCCCAGTGTGTTTGCATTGCATGTGGCATTTGACATTTCACAACTTGGCCTCTCAAAACTGGGATCCAGGATCAGCATGCAC
Target sequence
CTGCCTTCACCTAAATGCTAGTGACCTTATTGTAA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate