Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene191524703192139395192767764192155202192155588192123113192123251192146216192146251192167161192167178192181637192181649
FGF12 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016494
Fusion event
HBV-FGF12 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1474
End
1509
Orient
+
Integrated sequence
CTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTT
Host Sequence
Chromosome
chr3
Cytoband
q28
Reference genome
GRCh37/hg19
Start
191864005/192146216 (Hg38)
End
191864040/192146251 (Hg38)
Orient
+
Location type
Intronic
Target gene
FGF12
miRNAs that regulate target gene
hsa-mir-4668-5p ; hsa-mir-3613-3p ; hsa-mir-590-5p ; hsa-mir-21-5p
Nearest miRNA
hsa-let-7g/Upstream/2316207; hsa-mir-3137/Downstream/2988255;
Nearest TSS
ENST00000440867/Upstream/114007; ENST00000530635/Downstream/91786;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/282705, chr3-CpG: 177/Downstream/261781
Upstream sequence
aatgccctacacacatgaggtgtacagtccagtagaaaagataaacaataagcaaattaatagataatatgatgtccaataaggacttcaaaggaaaata
Downstream sequence
TAATTTTCATTAAAGTGTATAttttttttttttttttgagacggagtctcgctctatagcccaggctggagtgctttggtgctatctaggctcactgcaa
Target sequence
AGCTTCATCCAGGGATACTTGAGGAATAAATTTTC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate