Basic Information
VIS ID
TVIS10016498
Fusion event
HBV-chr4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1155
End
1190
Orient
-
Integrated sequence
CCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTG
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37/hg19
Start
52826975/51960809 (Hg38)
End
52827010/51960844 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-12113/Upstream/4308066; hsa-mir-1243/Downstream/751838;
Nearest TSS
ENST00000502981/Upstream/42037; ENST00000511875/Downstream/56776;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/115851, chr4-CpG: 75/Downstream/77041
Upstream sequence
AATCCTAGAATTCAGGACACATTTGTCATGCTTTGGTTTCCCTAGCACATGTCTCAGTTGCTTGATAAGTGGCTGTGGACATTGATAATGTCTCTGGGGA
Downstream sequence
GTCAAGGGTGAGCTAGATACCACCAGGGACCTAGAATCCCCAGGAATTCTTACCCAATTCCTTTAATAATACAATGACAGGTGTGTTTCCTTTCACCAAA
Target sequence
AAGGAAGGTATGAAGACTCAAGAGACTAAAGTGAA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate