Basic Information
VIS ID
TVIS10016499
Fusion event
HBV-DUX4L9 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1766
End
1801
Orient
-
Integrated sequence
TCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCT
Host Sequence
Chromosome
chr4
Cytoband
q35.2
Reference genome
GRCh37/hg19
Start
190943640/190022485 (Hg38)
End
190943675/190022520 (Hg38)
Orient
+
Location type
Intronic
Target gene
DUX4L9
Nearest miRNA
hsa-mir-12113/Upstream/5084045;
Nearest TSS
ENST00000502981/Upstream/61403; ENST00000630918/Downstream/4734;
Nearest CpG islands
chr4-CpG: 196/Target, None/Upstream, None/Downstream
Nearby gene
TUBB7P(-37651) ; FRG2(+1847) ;
Upstream sequence
agtgcccttttgatgcatgaaagttgtaaatttctgggatgatggaaatgttctatatcttaatagtgatatgtgctatgtggatatatgcatttgtcaa
Downstream sequence
TGGTGGCGATGCCCGGGTACGGGTTCCGCTCAAAGCAGGCTCGCAGGGCCTCGCTTTGGCTCGGGGTCCAAACGAGTCTCCGTCGCCGTCCTCGTCCCCG
Target sequence
CTCCGGAATGCCGATGGCCTGGGCCAGCCGTTCTC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate