Basic Information
VIS ID
TVIS10016500
Fusion event
HBV-LINC02217 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
831
End
866
Orient
-
Integrated sequence
ATTTAAACCCTAACAAAACAAAGAGATGGGGTTACT
Host Sequence
Chromosome
chr5
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
17430393/17430284 (Hg38)
End
17430428/17430319 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC02217
Nearest miRNA
hsa-mir-10397/Upstream/274292; hsa-mir-103a-1/Downstream/14505783;
Nearest TSS
ENST00000502646/Upstream/26138; ENST00000505844/Downstream/6418;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/75655, chr5-CpG: 30/Downstream/61029
Nearby gene
LINC02111(-43009) ; CDH18(+2042726) ;
Upstream sequence
tttgtatttttagtagagacagggtttcgccatgttggctaggctggtctctaactcctgacctcaggtgatccgcccaccttggcctcccaaagtgctg
Downstream sequence
tggctgttgggagcccagagtcctgaactcatcctgtgaccaagtgagtgagaatcattcaaaatcaggatgtcagcaccattctggcagcccaatcgca
Target sequence
acctcacatgcagctcgaacccaagagctggctga
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate