Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016502
Fusion event
HBV-UIMC1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1637
End
1672
Orient
+
Integrated sequence
TATTGCCCAAGGTCTTACATAAGAGGACTCTTGGAC
Host Sequence
Chromosome
chr5
Cytoband
q35.2
Reference genome
End
176406763/176979762 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10397/Upstream/350227; hsa-mir-1229/Downstream/2818516;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/92066, chr5-CpG: 128/Downstream/26091
Nearest cancer related gene
UIMC1(TSG, No orient, 0)
Upstream sequence
TCCCGATAGCAGGGCTGCCAAGAAAAAAGGTAAAAGGAAATGCCCAAGTATGTTAAGAATCTTGGAAAATGTCAAACATTGATATTATAACAAATGATGT
Downstream sequence
ACATATGTGCTGCTATAGAAAGGTCTCCCGGAAATACtataatggttaattttagtatcagtttgactggagtaagaaatacccagagaactagtaaagt
Target sequence
gcacattcctgtatgcataacatatATGACGTATG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.