Basic Information
VIS ID
TVIS10016506
Fusion event
HBV-LOC100505921 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1737
End
1772
Orient
-
Integrated sequence
GGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGT
Host Sequence
Chromosome
chr7
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
8005112/7965481 (Hg38)
End
8005147/7965516 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC100505921
Nearest miRNA
hsa-mir-339/Upstream/898436; hsa-mir-10399/Downstream/10161704;
Nearest TSS
ENST00000635602/Upstream/14772; ENST00000460897/Downstream/3278;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/324433, chr7-CpG: 81/Downstream/3710
Upstream sequence
cctcagcctcccaaagtgctgggattacaggcgtgagccaccatgcccggccaaatgcttattttttaacctaattatcctgcctatggtaatctgtcct
Downstream sequence
TCTGTTTAGTGTTCTCTCCCAGCCATGACCTCATTGCAAATACTGACAGCCTGGACTGCCTCTCAGATTTGGATGGGCCTTGGATGCTCAGCCAGGCAAA
Target sequence
GAGTTTAATCAGCTTAAGATGAACATCAGTGCAGA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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