Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016507
Fusion event
HBV-CREB5 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
863
End
898
Orient
-
Integrated sequence
TACTCTCTAAATTTTATGGGTTATGTCATTGGATGT
Host Sequence
Chromosome
chr7
Cytoband
p15.1
Reference genome
Start
End
28820411/28780794 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-204-5p ; hsa-mir-211-5p ; hsa-mir-125a-5p ; hsa-mir-10a-5p ; hsa-mir-32-5p ; hsa-mir-6832-3p ; hsa-mir-182-5p ; hsa-mir-8485 ; hsa-mir-607 ; hsa-mir-3671 ; hsa-mir-7853-5p ; hsa-mir-105-5p ; hsa-mir-1179 ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-147a ; hsa-mir-29b-2-5p ; hsa-mir-155-3p ; hsa-mir-6867-5p ; hsa-mir-644a ; hsa-mir-3911 ; hsa-mir-1273g-5p ; hsa-mir-203a-5p ; hsa-mir-92a-1-5p ; hsa-mir-374c-3p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-323b-3p ; hsa-mir-5195-5p ; hsa-mir-651-3p ; hsa-mir-590-5p ; hsa-mir-29c-3p ; hsa-mir-449a ; hsa-mir-128-3p ; hsa-mir-216a-3p ; hsa-mir-3681-3p ; hsa-mir-4672 ; hsa-mir-6768-5p
Nearest miRNA
hsa-mir-1183/Upstream/1611196; hsa-mir-10399/Downstream/899940;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/370806, chr7-CpG: 53/Downstream/73042
Upstream sequence
tgcctatggtaatctgtcctataaaaataaccaaaatatgaaaaaggctttatctacaaaaaggtcagccagagcattacacatagtaacaaaaggcagt
Downstream sequence
CAGCATACAAGATGATGCTTTTTTATTTCAGCATTCAGTAACTGCAGACTATTTTCTCCCTGTTTGCACTGTAGTTTTGTACACTGTGTAGTTTTGCATT
Target sequence
AACTCTTACTCTTGAAATGTACTGAAGCATTTACC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.