Basic Information
VIS ID
TVIS10016517
Fusion event
HBV-LOC107984125 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
3023
End
3058
Orient
-
Integrated sequence
CCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCT
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
55772918/54860358 (Hg38)
End
55772953/54860393 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC107984125
Nearest miRNA
hsa-mir-124-1/Upstream/11964083; hsa-mir-10400/Downstream/6854395;
Nearest TSS
ENST00000518652/Upstream/244291; ENST00000522559/Downstream/241996;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/238885, chr8-CpG: 222/Downstream/240703
Upstream sequence
TTAggccaggtgcagtggatcatgcctgtaatcccagcattttgggaggccgaggcgggcagaacacctgaggtcaggagtttgagaccagcctggccaa
Downstream sequence
CAAATACAGTTATGTCTAGGGTTATCTAACCACAAATGGAATATAGAAAGCTTCAGTAAAGACTCAAATTTGTAGCAAATTTGTAGAACTTCAAAacatt
Target sequence
AAGAAGAAGCCACATACAGTATTATTCTTTTAACC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate