Basic Information
VIS ID
TVIS10016521
Fusion event
HBV-chr8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
755
End
790
Orient
-
Integrated sequence
TTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTT
Host Sequence
Chromosome
chr8
Cytoband
q24.21
Reference genome
GRCh37/hg19
Start
129415529/128403283 (Hg38)
End
129415564/128403318 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1204/Upstream/253095; hsa-mir-10400/Downstream/1080739;
Nearest TSS
ENST00000518652/Upstream/306764; ENST00000519048/Downstream/562683;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/553305, chr8-CpG: 122/Downstream/1535808
Nearby gene
LINC00824(+1986) ;
Upstream sequence
TCAATTAAATTCCCAGGTCATGTCCATCCTCAACGACATACAAAGAAAATGCAAAATGTATTCTGAAGTATTCAATGTTTGCATCCGTCTGTTGGTGCAG
Downstream sequence
tataagAATAATGTAGTGGAATATTCCTATTTGAGGAGATTATAATCTAAAATAGGAGATGGGCATTAAAGAGGTTTACAAAATTATGACAAGTGCTGTG
Target sequence
caacatggaaagagcttagagcagtgactggtgta
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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