Basic Information
VIS ID
TVIS10016524
Fusion event
HBV-chr9 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1520
End
1555
Orient
-
Integrated sequence
ACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCT
Host Sequence
Chromosome
chr9
Cytoband
q22.33
Reference genome
GRCh37/hg19
Start
99460573/96698291 (Hg38)
End
99460608/96698326 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7a-1/Upstream/1612197; hsa-mir-12126/Downstream/665228;
Nearest TSS
ENST00000422679/Upstream/11235; ENST00000372322/Downstream/65367;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/10995, chr9-CpG: 51/Downstream/21294
Upstream sequence
ATATCTCTATCACCTATTGTTCTACAGGTTTTAACATGAGGGCTTTTAGTCTCtttttttttttgagacagaatctcactcggtcgccccggctccaggc
Downstream sequence
atttacaatagcatcaagaataataaaatacttaggaattaatttaaccaaggaagtaaaaaacttgtacactgaaaactacaaaccattgctgaaagac
Target sequence
ctacctttcttgagaaggaagttaataaaaatttc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate