Fusion event
HBV-COL15A1 integration
Disease
Hepatocellular carcinoma (HCC)
End
101797470/99035188 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7a-1/Upstream/805936; hsa-mir-12126/Downstream/7565740;
Upstream sequence
gtgtgtactcaactaacagagtttaacctttcttttgatagagcatttttgaaacactctttttgtaggatcagcaagtggacattttgtgtgctttgag
Downstream sequence
TGTGTACTAAGGGCTACTAGAAAGACCAGCTAGCTAAACCCTGGTCTCagggcagaggctgtgcggattcccctgtgagccgccagcttccaacaccaca
Target sequence
GGTACTTTTCCCCTTTTCTGTGGTTATAAAAATGA
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.